Skip to the main content

Vitamin and mineral levels

Folateand Red Cell Folate

Only one source here so far, and it found no clear difference in red Cell Folate.

How sure anyone can be

Low certainty, level 2 of 4

Further research is likely to change this.

The numbers reported

No number has been put on this yet. One source recorded only which way the numbers went — for now, that is all we have here.

One source, newest first

What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.

  • Randomised trial, 2021

    Low certainty, level 2 of 4

    Impact of high-dose folic acid supplementation in pregnancy on biomarkers of folate status and 1-carbon metabolism: An ancillary study of the Folic Acid Clinical Trial (FACT).

    Am J Clin Nutr. 2021;113(5):1361-1371. doi:10.1093/ajcn/nqaa407. PMID:33675351.

    Number reported
    Not in the abstract
    Which way it went
    No clear difference
    Likely range
    Not in the abstract
    Source’s own words
    no between-group difference reported; cohort median RBC folate was 2701 nmol/L
    Who was studied
    Pregnant
    Compared with
    low-dose folic acid (usual supplementation <=1.1 mg/d)
    Amount taken
    4 to 5.1 mg/d folic acid (4.0 mg high dose plus usual supplement <=1.1 mg, vs usual supplement alone)
    For how long
    56 to 126 days
    Disagreement between studies
    Not in the abstract
    Kind of record
    Journal article
    How this rating was reachedstarts at High, 2 steps down: risk of bias and imprecision
    1. Starts at High
    2. Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
    3. Imprecision brought it down to Lowthe abstract reports no confidence interval for the estimateNot in the abstract
    4. Ends at Low2 steps down.
    Checked, nothing to step it down for
    indirectness
    Inconsistency
    One study, so there was nothing to disagree

    Imprecision stops at the first check that applies; others may apply too.

    AI review could not confirm it — an AI agent re-read this finding against the saved source and at least one check failed. The batch record names the check and quotes the sentence that caused the doubt. No person read it.

    Read the abstract on PubMed

What is still missing from these readings

  • No number at all, only which way it went.
  • One gives no likely range, so how precise that number is is unknown.
  • One do not say how many people took part.

Something nobody wrote down is never a zero and never a guess.

Nothing left on our list for Folate

All eight things on our list for Folate have been read. That is rare here.

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

Read next

  • Folate

    Seven other questions read for it

  • Vitamin and mineral levels

    15 questions read under it

  • Red Cell Folate

    No other ingredients read against it

    Alphabetical, and by nothing else.

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.