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Hormones, thyroid and fertility

Iodineand Total Thyroxine (Total T4)

Only one source here so far, and it measured higher total Thyroxine (Total T4).

How sure anyone can be

Low certainty, level 2 of 4

Further research is likely to change this.

The numbers reported

40 percent change
percent higher mean total thyroxine at 24 weeks

None of these sources gave a likely range — the band the real answer probably sits in — so how precise these numbers are is still an open question here.

One source, newest first

What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.

  • Randomised trial, 2006 · 310 participants

    Low certainty, level 2 of 4

    Iodine supplementation improves cognition in iodine-deficient schoolchildren in Albania: a randomized, controlled, double-blind study.

    Am J Clin Nutr. 2006;83(1):108-14. doi:10.1093/ajcn/83.1.108. PMID:16400058.

    Number reported
    40 percent change
    Which way it went
    Higher
    Likely range
    Not in the abstract
    Source’s own words
    percent higher mean total thyroxine at 24 weeks
    Who was studied
    Child
    Compared with
    placebo
    Amount taken
    400 mg iodine, single oral dose of iodized oil
    For how long
    168 days
    Disagreement between studies
    Not in the abstract
    Kind of record
    Journal article
    How this rating was reachedstarts at High, 2 steps down: risk of bias and imprecision
    1. Starts at High
    2. Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
    3. Imprecision brought it down to Lowthe abstract reports no confidence interval for the estimateNot in the abstract
    4. Ends at Low2 steps down.
    Checked, nothing to step it down for
    indirectness
    Inconsistency
    One study, so there was nothing to disagree

    Imprecision stops at the first check that applies; others may apply too.

    AI review could not confirm it — an AI agent re-read this finding against the saved source and at least one check failed. The batch record names the check and quotes the sentence that caused the doubt. No person read it.

    Read the abstract on PubMed

What is still missing from these readings

  • One gives no likely range, so how precise that number is is unknown.

Something nobody wrote down is never a zero and never a guess.

Still to read for Iodine

One of the six things on our list for Iodine has no reading here yet:

  • Iodine, Serum

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

Read next

  • Iodine

    Four other questions read for it

  • Hormones, thyroid and fertility

    27 questions read under it

  • Total Thyroxine (Total T4)

    No other ingredients read against it

    Alphabetical, and by nothing else.

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.