Cholesterol and blood fats
Biotin (vitamin B7)and Total cholesterol
Two sources here, and they say different things: one measured lower total cholesterol and one found no clear difference.
How sure anyone can be
Low certainty, level 2 of 4Further research is likely to change this.
The most certain of the two findings here; each record carries its own.
The numbers reported
One source’s range, drawn against its own line of no difference and scaled to its own numbers.
-0.25-0.22 mmol/L-0.19
This range stays on one side of the no-difference line.
Two sources, newest first
We do not pick between these or average them into one number.
What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.
Systematic review, 2022
Low certainty, level 2 of 4Influence of biotin intervention on glycemic control and lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis.
Front Nutr. 2022;9:1046800. doi:10.3389/fnut.2022.1046800. PMID:36386951.
- Number reported
- -0.22 mmol/L
- Which way it went
- Lower
- Likely range
- -0.25 to -0.19
- Source’s own words
- mmol/L total cholesterol, mean difference vs control
- Who was studied
- Adult with type 2 diabetes
- Compared with
- control arm of randomised trials
- Amount taken
- Not in the abstract
- For how long
- 28 to 90 days
- Disagreement between studies
- Not in the abstract
- Kind of record
- Journal article
How this rating was reachedstarts at High, 2 steps down: risk of bias and imprecision
- Starts at High
- Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
- Imprecision brought it down to Lowthe abstract does not state how many participants were pooledNot in the abstract
- Ends at Low2 steps down.
- Checked, nothing to step it down for
- indirectness
- Inconsistency
- No disagreement reported, and no count of studies behind it
Imprecision stops at the first check that applies; others may apply too.
AI-reviewed & signed — an AI agent re-read this finding against the saved source and checked that the quote, the numbers, the units and the direction match it. No person read it. The owner authorised the agent to sign the batch with the owner's key, and every build rechecks that signature against these exact bytes.
Randomised trial, 2006
Low certainty, level 2 of 4Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia.
Biomed Pharmacother. 2006;60(4):182-5. doi:10.1016/j.biopha.2006.03.005. PMID:16677798.
- Number reported
- Not in the abstract
- Which way it went
- No clear difference
- Likely range
- Not in the abstract
- Source’s own words
- not reported
- Who was studied
- Adult with type 2 diabetes or hypertriglyceridemia
- Compared with
- placebo
- Amount taken
- 61.4 µmol/d
- For how long
- 28 days
- Disagreement between studies
- Not in the abstract
- Kind of record
- Journal article
How this rating was reachedstarts at High, 2 steps down: risk of bias and imprecision
- Starts at High
- Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
- Imprecision brought it down to Lowthe abstract reports no confidence interval for the estimateNot in the abstract
- Ends at Low2 steps down.
- Checked, nothing to step it down for
- indirectness
- Inconsistency
- One study, so there was nothing to disagree
Imprecision stops at the first check that applies; others may apply too.
AI-reviewed & signed — an AI agent re-read this finding against the saved source and checked that the quote, the numbers, the units and the direction match it. No person read it. The owner authorised the agent to sign the batch with the owner's key, and every build rechecks that signature against these exact bytes.
What is still missing from these readings
- One give no number at all, only which way it went.
- One gives no likely range, so how precise that number is is unknown.
- Two do not say how many people took part.
- Amount taken — One of Two readings: Not in the abstract.
Something nobody wrote down is never a zero and never a guess.
Still to read for Biotin (vitamin B7)
Four of the 13 things on our list for Biotin (vitamin B7) have no reading here yet:
- Fasting insulin
- Hair growth rate
- Hepatic Fat Fraction
- Vitamin B7 (Biotin)
Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.
Read next
Biotin (vitamin B7)
Eight other questions read for it
Cholesterol and blood fats
65 questions read under it
Total cholesterol
15 other ingredients read against it
First six, alphabetical, and by nothing else. The rest are on Cholesterol and blood fats.
This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.