Skip to the main content

Inflammation and oxidative stress

Boswellia serrataand Matrix Metalloproteinase-3 (Stromelysin-1)

Only one source here so far, and it measured lower matrix Metalloproteinase-3 (Stromelysin-1).

How sure anyone can be

Low certainty, level 2 of 4

Further research is likely to change this.

The numbers reported

No number has been put on this yet. One source recorded only which way the numbers went — for now, that is all we have here.

One source, newest first

What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.

  • Randomised trial, 2025

    Low certainty, level 2 of 4

    A Standardized Boswellia serrata Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study.

    J Am Nutr Assoc. 2025;44(5):375-386. doi:10.1080/27697061.2024.2438894. PMID:39700461.

    Number reported
    Not in the abstract
    Which way it went
    Lower
    Likely range
    Not in the abstract
    Source’s own words
    no magnitude reported in the abstract; significance only (p < 0.001 vs baseline and placebo)
    Who was studied
    Adult with knee osteoarthritis
    Compared with
    placebo
    Amount taken
    100 mg/d standardised Boswellia serrata extract
    For how long
    180 days
    Disagreement between studies
    Not in the abstract
    Kind of record
    Journal article
    How this rating was reachedstarts at High, 2 steps down: risk of bias and imprecision
    1. Starts at High
    2. Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
    3. Imprecision brought it down to Lowthe abstract reports no confidence interval for the estimateNot in the abstract
    4. Ends at Low2 steps down.
    Checked, nothing to step it down for
    indirectness
    Inconsistency
    One study, so there was nothing to disagree

    Imprecision stops at the first check that applies; others may apply too.

    AI review could not confirm it — an AI agent re-read this finding against the saved source and at least one check failed. The batch record names the check and quotes the sentence that caused the doubt. No person read it.

    Read the abstract on PubMed

What is still missing from these readings

  • No number at all, only which way it went.
  • One gives no likely range, so how precise that number is is unknown.
  • One do not say how many people took part.

Something nobody wrote down is never a zero and never a guess.

Still to read for Boswellia serrata

Eight of the 13 things on our list for Boswellia serrata have no reading here yet:

  • Alanine aminotransferase (ALT)
  • Equivalent Walking Distance
  • Erythrocyte Sedimentation Rate (ESR)
  • Forced Vital Capacity (FVC)
  • Hemoglobin
  • Peak Expiratory Flow Rate
  • Physical Function Score (SF-36 Physical Functioning)
  • Serum creatinine

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

Read next

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.