Topic

Inflammation and oxidative stress

Blood markers that move with inflammation or with oxidative stress.

This page is not a ranking. Ingredients appear in order of how much we have read here.

The 11 things measured here · ingredients read against each

Read here so far: 37 questions across 21 ingredients

Curcumin

Curcumin and High-sensitivity CRPTwo sources, all measured lowerModerate certainty, level 3 of 4
Curcumin and Interleukin-6One source, measured lowerModerate certainty, level 3 of 4
Curcumin and MalondialdehydeOne source, measured lowerModerate certainty, level 3 of 4
Curcumin and Superoxide Dismutase ActivityOne source, measured higherModerate certainty, level 3 of 4
Curcumin and Total Antioxidant CapacityOne source, measured higherModerate certainty, level 3 of 4
Curcumin and Tumor Necrosis Factor alpha (TNF-α)One source, measured lowerModerate certainty, level 3 of 4

N-acetylcysteine

N-acetylcysteine and High-sensitivity CRPTwo sources, saying different thingsLow certainty, level 2 of 4
N-acetylcysteine and HomocysteineOne source, measured lowerModerate certainty, level 3 of 4
N-acetylcysteine and MalondialdehydeOne source, measured lowerModerate certainty, level 3 of 4
N-acetylcysteine and Total Antioxidant CapacityOne source, found no clear differenceLow certainty, level 2 of 4

Selenium

Selenium and Glutathione Peroxidase ActivityOne source, measured higher, and one source carries a noticeLow certainty, level 2 of 4
Selenium and MalondialdehydeOne source, measured lower, and one source carries a noticeLow certainty, level 2 of 4
Selenium and Total Antioxidant CapacityOne source, measured higher, and one source carries a noticeLow certainty, level 2 of 4

Astaxanthin

Astaxanthin and MalondialdehydeOne source, found no clear differenceLow certainty, level 2 of 4
Astaxanthin and High-sensitivity CRPOne source, reported mixed resultsVery low certainty, level 1 of 4

Boron

Boron and High-sensitivity CRPOne source, measured lowerVery low certainty, level 1 of 4
Boron and Tumor Necrosis Factor alpha (TNF-α)One source, measured lowerVery low certainty, level 1 of 4

Copper

Copper and Superoxide Dismutase ActivityOne source, found no clear differenceLow certainty, level 2 of 4
Copper and Oxidative stress (F2-isoprostanes)One source, measured lowerVery low certainty, level 1 of 4

Ginger

Ginger and High-sensitivity CRPOne source, measured lowerVery low certainty, level 1 of 4
Ginger and Interleukin-6One source, found no clear differenceVery low certainty, level 1 of 4

Quercetin

Quercetin and High-sensitivity CRPOne source, measured lowerLow certainty, level 2 of 4
Quercetin and Tumor Necrosis Factor alpha (TNF-α)One source, found no clear differenceLow certainty, level 2 of 4

Taurine

Taurine and High-sensitivity CRPOne source, measured lowerLow certainty, level 2 of 4
Taurine and MalondialdehydeOne source, measured lowerLow certainty, level 2 of 4

Berberine

Berberine and High-sensitivity CRPTwo sources, all measured lowerVery low certainty, level 1 of 4

Boswellia serrata

Boswellia serrata and Matrix Metalloproteinase-3 (Stromelysin-1)One source, measured lowerLow certainty, level 2 of 4

Choline

Choline and HomocysteineOne source, measured lowerLow certainty, level 2 of 4

Coenzyme Q10

Coenzyme Q10 and High-sensitivity CRPOne source, measured lowerVery low certainty, level 1 of 4

Folate

Folate and HomocysteineOne source, measured lowerModerate certainty, level 3 of 4

Glycine

Glycine and Oxidative stress (F2-isoprostanes)One source, measured lowerVery low certainty, level 1 of 4

Lactobacillus rhamnosus GG

Lactobacillus rhamnosus GG and Interleukin-8 (IL-8)Two sources, saying different thingsVery low certainty, level 1 of 4

Melatonin

Melatonin and Oxidative stress (F2-isoprostanes)One source, measured lowerVery low certainty, level 1 of 4

Piperine

Piperine and High-sensitivity CRPThree sources, saying different thingsLow certainty, level 2 of 4

Vitamin B12

Vitamin B12 and HomocysteineOne source, measured lowerModerate certainty, level 3 of 4

Vitamin B6

Vitamin B6 and HomocysteineOne source, found no clear differenceLow certainty, level 2 of 4

Vitamin E

Vitamin E and MalondialdehydeOne source, measured lowerVery low certainty, level 1 of 4

Where the sources say different things

Every side in full, because one line would have to pick one of them.

Each bar is one source’s range, drawn against the line of no difference: left of the line is lower, right is higher. Widths are not comparable between rows.

Piperine and high-sensitivity CRP
Three sources here, and they say different things: two measured lower high-sensitivity CRP and one found no clear difference.
Low certainty, level 2 of 4The sources say different things
One source’s range. The sources here say different things. Randomised trial, 2015 · 117 participants
N-acetylcysteine and high-sensitivity CRP
Two sources here, and they say different things: one measured lower high-sensitivity CRP and one found no clear difference.
Low certainty, level 2 of 4The sources say different things
One source’s range, crossing no difference: these numbers fit no effect too. The sources here say different things. Systematic review, 2020
Lactobacillus rhamnosus GG and interleukin-8 (IL-8)
Two sources here, and they say different things: one measured lower interleukin-8 (IL-8) and one reported mixed results.
Very low certainty, level 1 of 4The sources say different things
-66 percent change
Mechanism study, 2008

How much of this is one source

Read from 30 sources. 32 of the 37 questions here rest on a single source with nothing yet to check them against, and on 3 questions the sources say different things.

What is still to read is kept per ingredient, not per topic, so every ingredient named above carries its own list.

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

The other 14 topics

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.