Skip to the main content

Bone strength

Vitamin K2 (menaquinone-7)and Bone mineral density

Only one source here so far, and it measured higher bone mineral density.

How sure anyone can be

Low certainty, level 2 of 4

Further research is likely to change this.

The numbers reported

No number has been put on this yet. One source recorded only which way the numbers went — for now, that is all we have here.

One source, newest first

What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.

  • Systematic review, 2015 · 19 studies pooled

    Low certainty, level 2 of 4

    Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.

    Osteoporos Int. 2015;26(3):1175-86. doi:10.1007/s00198-014-2989-6. PMID:25516361.

    Number reported
    Not in the abstract
    Which way it went
    Higher
    Likely range
    Not in the abstract
    Source’s own words
    vertebral BMD; the abstract reports significance only, with no pooled mean difference
    Who was studied
    Postmenopausal women with osteoporosis
    Compared with
    control
    Amount taken
    Not in the abstract
    For how long
    Not in the abstract
    Disagreement between studies
    fracture pooling was heterogeneity-driven: RR 0.63 (p = 0.08) overall, RR 0.50 (p = 0.0005) after removing the heterogeneous study
    Kind of record
    Journal article
    How this rating was reachedstarts at High, 2 steps down: risk of bias and imprecision
    1. Starts at High
    2. Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
    3. Imprecision brought it down to Lowthe abstract reports no confidence interval for the estimateNot in the abstract
    4. Ends at Low2 steps down.
    Checked, nothing to step it down for
    indirectness
    Inconsistency
    No high disagreement reported between the 19 studies it pooled

    Imprecision stops at the first check that applies; others may apply too.

    AI review could not confirm it — an AI agent re-read this finding against the saved source and at least one check failed. The batch record names the check and quotes the sentence that caused the doubt. No person read it.

    Read the abstract on PubMed

What is still missing from these readings

  • No number at all, only which way it went.
  • One gives no likely range, so how precise that number is is unknown.
  • One do not say how many people took part.
  • Amount taken — Not in the abstract.
  • For how long — Not in the abstract.

Something nobody wrote down is never a zero and never a guess.

Still to read for Vitamin K2 (menaquinone-7)

One of the nine things on our list for Vitamin K2 (menaquinone-7) has no reading here yet:

  • Serum menaquinone-7 (MK-7)

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

Read next

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.