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Open WellbeingWhat the studies actually measured

Inflammation and oxidative stress

Astaxanthinand High-sensitivity CRP

Only one source here so far, and it reported mixed results for high-sensitivity CRP.

How sure anyone can be

Very low certainty, level 1 of 4

Any estimate here is very uncertain.

The numbers reported

One source’s range, drawn against its own line of no difference and scaled to its own numbers.

-0.99-0.528 mg/L-0.066

This range stays on one side of the no-difference line.

Bar the confidence interval — the range the true effect is likely to sit inNotch the number the source reportedLine where there would be no difference at all

One source, newest first

What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.

  • Systematic review, 2020

    Very low certainty, level 1 of 4

    The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.

    Pharmacol Res. 2020;161:105113. doi:10.1016/j.phrs.2020.105113. PMID:32755613.

    Number reported
    -0.528 mg/L
    Which way it went
    Mixed results
    Likely range
    -0.99 to -0.066
    Source’s own words
    mg/L CRP, weighted mean difference vs control, trials of 12 weeks or longer only
    Who was studied
    Adult
    Compared with
    placebo or control
    Amount taken
    Not in the abstract
    For how long
    84 days (upper bound: Not in the abstract)
    Disagreement between studies
    Not in the abstract
    Kind of record
    Journal article
    How this rating was reachedstarts at High, 4 steps down: risk of bias, indirectness, imprecision and inconsistency
    1. Starts at High
    2. Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
    3. Indirectness brought it down to Lowthe outcome measured is a proxy for the target outcomeReported in the abstract
    4. Imprecision brought it down to Very lowthe abstract does not state how many participants were pooledNot in the abstract
    5. Inconsistency — already at Very low, the lowest rungpooled studies disagree on the direction of effectReported in the abstract
    6. Ends at Very low4 steps down.

    Imprecision stops at the first check that applies; others may apply too.

    AI review could not confirm it — an AI agent re-read this finding against the saved source and at least one check failed. The batch record names the check and quotes the sentence that caused the doubt. No person read it.

    Read the abstract on PubMed

What is still missing from these readings

  • One do not say how many people took part.
  • Amount taken — Not in the abstract.

Something nobody wrote down is never a zero and never a guess.

Still to read for Astaxanthin

Eight of the 17 things on our list for Astaxanthin have no reading here yet:

  • Diastolic blood pressure
  • Endurance Performance (Time to Exhaustion)
  • Fasting insulin
  • Heart Rate (Continuous)
  • Hemoglobin A1c
  • LDL cholesterol
  • Systolic blood pressure
  • Total cholesterol

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

Read next

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.