Heart and blood pressure
Calciumand Systolic blood pressure
Only one source here so far, and it measured lower systolic blood pressure.
How sure anyone can be
Moderate certainty, level 3 of 4Further research may change this.
The numbers reported
One source’s range, drawn against its own line of no difference and scaled to its own numbers.
-2.08-1.37 mmHg-0.66
This range stays on one side of the no-difference line.
One source, newest first
What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.
Systematic review, 2022 · 18 studies pooled · 3,140 participants
Moderate certainty, level 3 of 4Calcium supplementation for prevention of primary hypertension.
Cochrane Database Syst Rev. 2022;1(1):CD010037. doi:10.1002/14651858.CD010037.pub4. PMID:35014026.
This source later carried a notice: Update of Cochrane Database Syst Rev. 2021 Aug 10;8:CD010037. doi: 10.1002/14651858.CD010037.pub3. The number below is exactly as the source gave it.
- Number reported
- -1.37 mmHg
- Which way it went
- Lower
- Likely range
- -2.08 to -0.66
- Source’s own words
- mm Hg mean difference in systolic blood pressure vs placebo/control
- Who was studied
- Normotensive people
- Compared with
- placebo or control
- Amount taken
- Pooled across dose bands — one amount does not apply
- For how long
- Not in the abstract
- Disagreement between studies
- I2 = 0%
- Kind of record
- Journal article
Results by amount
The source pooled a separate result for each reported amount band.
doses less than 1000 mg
- Number reported
- -0.02 mmHg
- Likely range
- -2.23 to 2.2 mmHg
- People who took part
- 302
- Studies pooled
- 3
- Disagreement between studies
- I2 = 0%
- Source-reported certainty
- Moderate
doses 1000 to 1500 mg
- Number reported
- -1.05 mmHg
- Likely range
- -1.91 to -0.19 mmHg
- People who took part
- 2,488
- Studies pooled
- 9
- Disagreement between studies
- I2 = 0%
- Source-reported certainty
- High
doses more than 1500 mg
- Number reported
- -2.79 mmHg
- Likely range
- -4.71 to 0.86 mmHg
- People who took part
- 350
- Studies pooled
- 7
- Disagreement between studies
- I2 = 0%
- Source-reported certainty
- Moderate
How this rating was reachedstarts at High, one step down: imprecision
- Starts at High
- Imprecision brought it down to Moderatethe interval excludes no effect but spans a 3-fold range of effect size, from trivial to largeReported in the abstract
- Ends at ModerateOne step down.
- Checked, nothing to step it down for
- risk of bias and indirectness
- Inconsistency
- No high disagreement reported between the 18 studies it pooled
Imprecision stops at the first check that applies; others may apply too.
Source saved; quote checked byte-for-byte against it by software; no signature.
What is still missing from these readings
- For how long — Not in the abstract.
Something nobody wrote down is never a zero and never a guess.
Still to read for Calcium
Three of the nine things on our list for Calcium have no reading here yet:
- HDL cholesterol
- LDL cholesterol
- Parathyroid Hormone (PTH)
Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.
Read next
Calcium
Five other questions read for it
Heart and blood pressure
49 questions read under it
Systolic blood pressure
15 other ingredients read against it
First six, alphabetical, and by nothing else. The rest are on Heart and blood pressure.
This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.