Skip to the main content
Open WellbeingWhat the studies actually measured

Heart and blood pressure

Vitamin K2 (menaquinone-7)and Dephospho-uncarboxylated MGP (dp-ucMGP)

Only one source here so far, and it measured lower dephospho-uncarboxylated MGP (dp-ucMGP).

How sure anyone can be

Low certainty, level 2 of 4

Further research is likely to change this.

The numbers reported

-50 percent change
% relative reduction in circulating dp-ucMGP vs placebo

None of these sources gave a likely range — the band the real answer probably sits in — so how precise these numbers are is still an open question here.

One source, newest first

What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.

  • Randomised trial, 2015 · 244 participants

    Low certainty, level 2 of 4

    Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.

    Thromb Haemost. 2015;113(5):1135-44. doi:10.1160/TH14-08-0675. PMID:25694037.

    Number reported
    -50 percent change
    Which way it went
    Lower
    Likely range
    Not in the abstract
    Source’s own words
    % relative reduction in circulating dp-ucMGP vs placebo
    Who was studied
    Postmenopausal women
    Compared with
    placebo
    Amount taken
    180 microg/d MK-7
    For how long
    1,095 days
    Disagreement between studies
    Not in the abstract
    Kind of record
    Journal article
    How this rating was reachedstarts at High, 2 steps down: risk of bias and imprecision
    1. Starts at High
    2. Risk of bias brought it down to Moderatethe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
    3. Imprecision brought it down to Lowthe abstract reports no confidence interval for the estimateNot in the abstract
    4. Ends at Low2 steps down.
    Checked, nothing to step it down for
    indirectness
    Inconsistency
    One study, so there was nothing to disagree

    Imprecision stops at the first check that applies; others may apply too.

    AI-reviewed & signed — an AI agent re-read this finding against the saved source and checked that the quote, the numbers, the units and the direction match it. No person read it. The owner authorised the agent to sign the batch with the owner's key, and every build rechecks that signature against these exact bytes.

    Read the abstract on PubMed

What is still missing from these readings

  • One gives no likely range, so how precise that number is is unknown.

Something nobody wrote down is never a zero and never a guess.

Still to read for Vitamin K2 (menaquinone-7)

One of the nine things on our list for Vitamin K2 (menaquinone-7) has no reading here yet:

  • Serum menaquinone-7 (MK-7)

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

Read next

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.