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Heart and blood pressure

Magnesiumand Major cardiovascular events

Only one source here so far, and it found no clear difference in major cardiovascular events.

How sure anyone can be

Very low certainty, level 1 of 4

Any estimate here is very uncertain.

The numbers reported

One source’s range, drawn against its own line of no difference and scaled to its own numbers.

0.880.99 risk ratio1.1

This range crosses the no-difference line, so these numbers fit a real difference and no difference at all equally well.

Bar the confidence interval — the range the true effect is likely to sit inNotch the number the source reportedLine where there would be no difference at all

One source, newest first

What we read is the published abstract, not the full paper, so a blank below may still be printed in the paper itself. A fixed rule worked this out from the source’s own fields. Nobody checked this rating by hand.

  • Cohort study, 2016 · 40 studies pooled

    Very low certainty, level 1 of 4

    Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose-response meta-analysis of prospective cohort studies.

    BMC Med. 2016;14(1):210. doi:10.1186/s12916-016-0742-z. PMID:27927203.

    Number reported
    0.99 risk ratio
    Which way it went
    No clear difference
    Likely range
    0.88 to 1.1
    Source’s own words
    relative risk of total cardiovascular disease per 100 mg/day increment in dietary magnesium
    Who was studied
    Adult
    Compared with
    lower dietary magnesium intake (per 100 mg/day increment)
    Amount taken
    100 mg/d increment in dietary magnesium intake (upper bound: Not in the abstract)
    For how long
    Not in the abstract
    Disagreement between studies
    Not in the abstract
    Kind of record
    Journal article
    How this rating was reachedstarts at Low, 2 steps down: risk of bias and imprecision
    1. Starts at Low
    2. Risk of bias brought it down to Very lowthe abstract reports no risk-of-bias or quality appraisal, so study limitations cannot be ruled outNot in the abstract
    3. Imprecision — already at Very low, the lowest rungthe confidence interval includes no effectReported in the abstract
    4. Ends at Very low2 steps down.
    Checked, nothing to step it down for
    indirectness
    Inconsistency
    No high disagreement reported between the 40 studies it pooled

    Imprecision stops at the first check that applies; others may apply too.

    AI review could not confirm it — an AI agent re-read this finding against the saved source and at least one check failed. The batch record names the check and quotes the sentence that caused the doubt. No person read it.

    Read the abstract on PubMed

What is still missing from these readings

  • One do not say how many people took part.
  • For how long — Not in the abstract.

Something nobody wrote down is never a zero and never a guess.

Still to read for Magnesium

11 of the 21 things on our list for Magnesium have no reading here yet:

  • Atrial fibrillation incidence
  • Bone mineral density
  • Cognitive performance
  • Depression
  • Fasting insulin
  • Generalized Anxiety Disorder-7 (GAD-7)
  • Hemoglobin A1c
  • Insomnia Severity Index
  • Patient Health Questionnaire-9 (PHQ-9)
  • Sleep efficiency
  • Total testosterone

Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.

Read next

This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.